Restoring Salivary Glands Function with Gene Transfer Therapy: Turning the Impossible into Reality

Michael Passineau, PhD

Friday, May 1
1:30 PM – 3:00 PM

Moderator:
Chelsia Sim, BDS, MSc

Description

Permanent destruction of salivary glands is one of the significant negative consequence of head and neck radiation therapy and Sjögren syndrome that is tied to a variety of critical oral health issues. This talk sheds light on the promising approach of gene transfer therapy to restore damaged salivary glands.

Learning Objectives

1. Describe the fundamental concepts of salivary glands gene therapy.
2. Discuss the various techniques of salivary glands gene transfer in both in vitro and in vivo studies.
3. Demonstrate the future directions and the applicability of translating this treatment modality to randomized clinical trials.